The effectiveness of “Marbo with red line” has been tested on: 1) patients suffering from various, benign, forms of alopecia areata, 2) patients with negative prognosis (ophiasis), and 3) on patients suffering from total (malign) form of the disease. Retrospective examination performed from 1992 to 1998, comprised 437 patients of both sexes with different topografic disposition of the patches on a scalp.
Benign form of the disease was diagnosed in 376 cases (86,04%), ophiasis in 54 cases (12,36%), and total (malign) form in 7 cases(1,60%).
Out of the total of 437 examined cases (100%), the effectiveness could not be examined in 89 (29,36%) because those patients did not come to checkups. There were 67 benign cases (72,58%), 20 ophiasis (22,47%), and 2 cases of malign form of the disease (2,25%).
In the first group of the benign cases, out of 309 examinees, the effectiveness was confirmed in 211 (68,29%) cases, in 53 cases (17,15%) the therapy stimulated the renewal of follicles – in fact the appearance of velus hair and “swollen follicles”, and in 45 cases (14,56%) the clinical picture was unchanged.
In the group of patients with the second type of alopecia areata – ophasis – out of 34 cases, the effectiveness of the activator was proved in 19 cases (55,90%), in 8 cases the therapy stimulated the renewal of follicles – the appearance of velus hair and “swollen follicles”, and in 2 cases (40%) the clinical picture was unchanged.
Note:
In a periode between 1991 till 2001 more then 1000 users of "Marbo activator" complitily recover thair hair.


| Patient R.S. (Year of Birth: 1956, Place: Belgrade) | |
| Medical History | Started losing hair a few months before coming to Marbo Clinic, pa bald patch 5x5 cm. |
| First visit to "Marbo" Clinic: 07.02.2000 | |
| Objective finding | A bald patch on the back of the head, size 5x5 cm, tendency to spread. |
| Diagnosis | Alopecia Areata |
| Treatment | Aktivator Marbo |
| Final checkup: 03.08.2003 | Hair completely grown. Normal pigmentation and thickness. |


| Patient D.N. (Year f Birth: 1983, Place: Pancevo) | |
| Medical History | 1999. - first patches appeared, size 3 and 2 cm. Was unsuccessfully treated in Dermatological Clinic |
| First visit to "Marbo" Clinic: 08.02.2000 | |
| Objective finding | Patches - size 2x2 and 3x2 cm u temporal area. .Hair does not fall out around them, but it is thinner. |
| Diagnosis | Alopecia Areata multilocularis |
| Treatment | Activator Marbo, checkup in 2 months. |
| Checkup: 17.04.2000 | New hair seen in the bold areas, normal pigmentation towards the centre. |
| Final checkup: 16.08.2000 | Hair fully grown. .All areas covered with normally pigmented hair. |


| Patient R.S.(Year of Birth - 1965, Place: Belgrade) | |
| Medical History | June 1999, a bald patch on the back of the head. After numerous attempts to treat it, the patient comes to “Marbo” Dermatological Clinic. |
| First visit to "Marbo" Clinic: 04.02.2000 | |
| Objective finding | A bald patch size 2x2 cm. On the back of the head. Hair around it stable.. |
| Diagnosis | Alopecia Areata |
| Treatment | Activator Marbo, check up in one month. |
| Check up 09.03.2000 | Scattered, pigmented hairs appeared on the patch. |
| Final checkup: 05.04.2000 | Alopetic patches completely covered with dark hair. |


| Patient M.I. (Year of Birth - 1994, Place: Belgrade) | |
| Medical History | In Septembre 1999. the first bald patch appeared, size of a fingernail. After a month, the patch grew bigger - . 5x5cm. Patient first treated in IDV KSS with Sinoderm(2x1gr / 15 days), then without any results. |
| First visit to "Marbo"Clinic: 18.12.1999 | |
| Objective finding | A patch on the back of the head, size 4x4 cm. On the edges, hairs fall out. |
| Diagnosis | Alopecia Areata multilocularis |
| Treatment | Activator Marbo, check up in 40 days |
| Checkup: 08.02.2000 | Visible hair growth in the whole of the area. Check up in one month. |
| Checkup: 10.03.2000 | The entire bald area covered with fair hair Check up in one month. |
| Final checkup: 15.04.2000 | Hair fully grown, normal pigmentation. |


| Patient B.T.(Year of Birth - 1987, Place: Belgrade) | |
| Medical History | First bald patches appeared in 1999. On the back of the head, size 4x3 cm. She started treatment In Vrsac for 2 months, but there were no results. Three months later the hair started falling out in the and she got crusts and folliculitis everywhere. |
| First visit to "Marbo"Clinic: 18.12.1999 | |
| Objective finding | A bald patch on the back of the head. size 4x3 cm. In the parting area hair thinner. |
| Diagnosis | Alopecia Areata |
| Treatment | Activator Marbo, check up in 2 months |
| Check up: 03.02.2000 | A new hair appeared on the left side. |
| Check up: 09.04.2000 | Hair (0.3 cm) fully grown on the right side. Hair slightly grown in the frontal area. Check up in 2 months. |
| Check up: 17.06.2000 | Hair completely grown on all alopetic areas apart from the left, frontal area. |
| Final checkup | Hair completely grown. |


| Patient M.L.(Year of Birth - 1987, Place: Belgrade) | |
| Medical History | In May 1999. a patch without hair appeared in the right, parietal area. Two months later, new hair grown. In October 1999, hair loss again, in the frontal parietal area.Eye lashes fell out. |
| First visit to "Marbo"Clinic: 14.12.1999 | |
| Objective finding | A bald patch size 10x10 cm in the frontal parietal area. |
| Diagnosis | Alopecia Areata |
| Treatment | Aktivator Marbo, check up in 2 months. |
| Check up: 24.02.2000 | New, fine hair grown. |
| Final check up: 17.04.2000 | Hair completely grown. Advised further hair care. |


| Patient: M.M. (Year of Birth: 1999, Place: Belgrade) | |
| Medical History | First bald patches appeared in January 2005, with tendency to spread. |
| First visit to „Marbo“ Clinic: 10.06.2005 | |
| Objective finding | Clinical prognosis negative, because the disease spread to a back of the head (ophiasis) |
| Diagnosis | Alopecia areata |
| Treatment | Activator Marbo |
| Final checkup: 17.01.2006 | Hair fully grown. |


| Patient: N.D. (Year of Birth: 1994, Place: Belgrade) | |
| Medical History | First bald areas appeared in June 2003, with tendency of spreading and complete hair loss in the right parietal area.Clinical treatment was unsuccessful. |
| First visit to „Marbo“ Clinic: 03.12.2004 | |
| Objective finding | photo document |
| Diagnosis | Alopecia areata |
| Treatment | Activator Marbo |
| Checkup: 06.01.2005 | Hair growth in the whole bald area after one dose of Activator, the treatment continued. |
| Final checkup: 26.02.2005 | Hair fully grown. |


| Patient: M.Z. (Year of Birth: 1948, Place: Negotin) | |
| Medical History | After the diagnosis of Alopecia Areata multiokularis she was treated in the clinic, but without results. |
| First visit to „Marbo“ Clinic: 11.05.2005 | |
| Objective finding | photo document |
| Diagnosis | Alopecia Areata multiokularis |
| Treatment | Activator Marbo |
| Final checkup: 17.01.2006 | Hair fully grown. |


| Patient: M.D. (Year of Birth: 1971, Place: Novi Sad) | |
| Medical History | First patches appeared in 1991, with tendency to spread. |
| First visit to „Marbo“ Clinic: 10.09.1993 | |
| Objective finding | photo document |
| Diagnosis | Alopecia areata |
| Treatment | Activator Marbo |
| Final checkup: 15.02.1994 | Hair fully grown. |


| Patient: G.S. (Year of Birth: 1982, Place: Belgrade) | |
| Medical History | First patches appeared in 1993. Seven years of clinical treatment gave no results. |
| First visit to „Marbo“ Clinic: 12.04.2000 | |
| Objective finding | Total hair loss, including eyebrows and eyelashes. |
| Diagnosis | Alopecia areata totalis |
| Treatment | Activator Marbo |
| Checkup: 2001 | Visible hair growth in the whole area. |
| Final checkup: | Was not done, because the patient changed the address, we tried to contact her in 2002. |